araldite-2011-sds

SAFETY DATA SHEET According to REACH Regulation (EC) No 1907/2006, as amended by UK REACH Regulations SI 2019/758 ARALDITE® 2011 HARDENER

Version 1 . 1

Revision Date: 27.09.2021

SDS Number: 400001015904

Date of last issue: 24.01.2018 Date of first issue: 24.01.2018

Print Date 14.09.2022

: Test Type: reverse mutation assay Test system: Salmonella typhimurium Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 471 Result: negative : Test Type: In vitro mammalian cell gene mutation test Test system: mouse lymphoma cells Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 476 Result: negative GLP: yes : Test Type: reverse mutation assay Test system: Salmonella tryphimurium and E. coli Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 471 Result: negative

Amines, polyethylenepoly-, triethylenetetramine fraction : Genotoxicity in vitro

: Test Type: In vitro mammalian cell gene mutation test Test system: Chinese hamster ovary cells Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 476 Result: positive

Components: Amines, polyethylenepoly-, triethylenetetramine fraction : Genotoxicity in vivo

: Test Type: In vivo micronucleus test Test species: Mouse (male and female) Cell type: Bone marrow Application Route: Intraperitoneal injection Dose: 0 - 600 mg/kg Method: OECD Test Guideline 474 Result: negative

Germ cell mutagenicity- Assessment

: No data available

Carcinogenicity

Components: N'-(3-aminopropyl)-N,N-dimethylpropane-1,3-diamine : Species: Mouse, male Application Route: Dermal Exposure time: 20 month(s) Dose: 1.25/56.3 mg/animal Frequency of Treatment: 3 daily No observed adverse effect level: >= 56.3 mg/kg body weight

SDS_GB-AM – 6N – 400001015904

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